Cd34 Mouse Monoclonal Antibody [Clone ID: QBEND/10]

CAT#: TA327637

Mouse Monoclonal CD34 Antibody

Product Images

Immunohistochemistry staining of Paraffin Tonsil, placenta tissue by CD34 antibody (dilution: 1:50 - 1:200; visualization of staining: Membranous)

Specifications

Product Data

• Clone Name: QBEND/10
• Applications: IHC
• Recommended Dilution: IHC: 1:50 - 1:200
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Formulation: This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: CD34 antigen
• Database Link:
  NP_001104529
  Entrez Gene 947 Human
  UniProt ID Q64314
• Synonyms: CD34
• Note: Anti-CD34 recognizes a cell surface antigen of approximately 110 kD that is expressed selectively on human hematopoietic progenitor cells, including myeloid and lymphoid lineage progenitors. It is a marker of choice for identifying and counting the blasts in acute myeloid leukemia. In addition, this marker is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule in greater amounts than non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi’s sarcoma, but shows low specificity.