CD2 Mouse Monoclonal Antibody [Clone ID: MRQ-11]

CAT#: TA327625

Mouse Monoclonal CD2 Antibody

Product Images

Immunohistochemistry staining of Paraffin Tonsil tissue by CD2 antibody (dilution: 1:10 - 1:50; visualization of staining: Cytoplasmic, membranous)

Specifications

Product Data

• Clone Name: MRQ-11
• Applications: IHC
• Recommended Dilution: IHC: 1:10 - 1:50
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Formulation: This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: CD2 molecule
• Database Link:
  NP_001758
  Entrez Gene 914 Human
  UniProt ID P06729
• Synonyms: LFA-2; SRBC; T11
• Note: CD2 is one of the earliest T-cell lineage restricted antigens to appear during T-cell differentiation and only rare CD2+ cells can be found in the bone marrow. Anti-CD2 is a pan-T-cell antigen marker.Anti-CD2 is therefore useful for the identification of virtually all normal T-lymphocytes. It is also very useful in the assessment of lymphoid malignancies as it is expressed in the majority of precursor and mature T-cell lymphomas and leukemias. As with other pan-T-cell antigens, CD2 may be aberrantly deleted in some neoplastic T-cell populations, especially peripheral T-cell lymphomas. When combined with anti-CD25, anti-CD2 may assist in the diagnosis of systemic mastocytosis and mastocytic leukemia.

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Hematopoietic cell lineage