Kcnip2 Mouse Monoclonal Antibody [Clone ID: S60-73]

CAT#: TA326563

Mouse Monoclonal Anti-KChiP2 Antibody

Product Images

Western blot analysis on rat brain membrane tissues using a 1:1000 dilution of the antibody

• 

  IHC analysis of KChIP2 in frozen sections of mouse brain extract using the antibody

Specifications

Product Data

• Clone Name: S60-73
• Applications: IHC, WB
• Recommended Dilution: WB: 1ug/ml, IHC: 0.1-1ug/ml, IF: 1-10ug/ml
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Fusion protein amino acids 1-252 (Full length) of rat KChIP2b
• Formulation: PBS pH7.4, 50% glycerol
• Concentration: lot specific
• Purification: Protein G Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: Kv channel-interacting protein 2
• Database Link:
  NP_001029133
  Entrez Gene 30819 HumanEntrez Gene 80906 MouseEntrez Gene 56817 Rat
  UniProt ID Q9JM59
• Background: There are four member of the KChiPs (Kv4 potassium channel interacting protein) family. They are all EF handcontaining proteins required for the traffic of channelforming Kv4 K+ subunits to the plasma membrane . KChiP2 expression has been found to be significantly decreased in hypertrophy and heart failure , and does so thru modulatin of intracellular concentration and calcineurin/NFAT pathways . It has also been found that KChiP2 also functionally modulates the Cav1.2 goverened Ltype calcium channel through a direct interaction between KChiP2 and the amino-terminus of Cav1.2 .
• Synonyms: DKFZp566L1246; KCHIP2; MGC17241
• Note: Detects ~35kDa. No cross-reactivity against rat KCHiPs 1, 3