Cyclin D3 (CCND3) Rabbit Polyclonal Antibody

CAT#: TA325312

Rabbit Polyclonal Cyclin D1 (Thr286) Antibody (Phospho-specific)

Product Images

Western blot analysis of extracts from Jurkat cells, using Cyclin D1 (Phospho-Thr286) Antibody. The lane on the left is treated with the synthesized peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000; IHC: 1:50-1:200; IF/ICC: 1:100-1:500
• Reactivities: Mouse, Rat, Human
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized peptide derived from human Cyclin D1 around the phosphorylation site of Thr286.
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 33 kDa
• Gene Name: cyclin D3
• Database Link:
  NP_001129489
  Entrez Gene 12445 MouseEntrez Gene 25193 RatEntrez Gene 896 Human
  UniProt ID P30281
• Background: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event.
• Synonyms: cyclin D3; D3-type cyclin; G1; OTTHUMP00000016390; S-specific cyclin D3

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle, Focal adhesion, Jak-STAT signaling pathway, p53 signaling pathway, Wnt signaling pathway