OASL Rabbit Polyclonal Antibody

CAT#: TA324251

Anti-OASL Rabbit Polyclonal Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: Jurkat cells Primary antibody: TA324251 (OASL Antibody) at dilution 1/300 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 3 minutes

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  Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using TA324251 (OASL Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using TA324251 (OASL Antibody) at dilution 1/20, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Jurkat cells
  IHC: 25-100
  Positive control: Human gasrtic cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to C terminal 207 amino acids of human 2'-5'-oligoadenylate synthetase-like
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 59 kDa
• Gene Name: 2'-5'-oligoadenylate synthetase like
• Database Link:
  NP_001248754
  Entrez Gene 8638 Human
  UniProt ID Q15646
• Background: OASL encodes an interferon-induced protein that is a member of the 2-5A synthetase family. 2-prime;5-prime oligoadenylates (2-5As) bind to and activate RNase L; resulting in general RNA degradation and consequent inhibition of protein synthesis. 2-5As are produced by a well-conserved family of interferon-induced enzymes; the 2-5A synthetases or OASs
• Synonyms: OASLd; p59 OASL; p59-OASL; p59OASL; TRIP-14; TRIP14

Reference Data

• Protein Families: Druggable Genome