NMDAR1 (GRIN1) Rabbit Polyclonal Antibody

CAT#: TA323550

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Anti-GRIN1 Rabbit Polyclonal Antibody



USD 345.00


Availability*
In Stock

Size
    • 100 ul


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Specifications

Product Data
Applications IHC
Recommended Dilution ELISA: 1:2000-5000, IHC: 1:25-100
Reactivity Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 35-49 amino acids of human glutamate receptor, ionotropic, N-methyl D-aspartate 1
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name glutamate ionotropic receptor NMDA type subunit 1
Background The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors; members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses; which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms; possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.
Synonyms GluN1; MRD8; NMD-R1; NMDA1; NMDAR1; NR1
Reference Data
Protein Families Druggable Genome, Ion Channels: Glutamate Receptors, Transmembrane
Protein Pathways Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Huntington's disease, Long-term potentiation, Neuroactive ligand-receptor interaction
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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