AMD1 Rabbit Polyclonal Antibody

CAT#: TA323400

Anti-AMD1 Rabbit Polyclonal Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using TA323400 (AMD1 Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using TA323400 (AMD1 Antibody) at dilution 1/20, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA323400 (AMD1 Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA323400 (AMD1 Antibody) at dilution 1/20, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human gasrtic cancer
  Predicted cell location: Nucleus, Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 298-310 amino acids of human adenosylmethionine decarboxylase 1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: adenosylmethionine decarboxylase 1
• Database Link:
  NP_001625
  Entrez Gene 11702 MouseEntrez Gene 81640 RatEntrez Gene 262 Human
  UniProt ID P17707
• Background: This gene encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine; spermidine; and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Two alternatively spliced transcript variants that encode different proteins have been identified. Pseudogenes of this gene are found on chromosomes 5; 6; 10; X and Y.
• Synonyms: ADOMETDC; AMD; SAMDC

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Arginine and proline metabolism, Cysteine and methionine metabolism, Metabolic pathways