IL18R Beta (IL18RAP) Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | WB |
Recommended Dilution | WB: 500-2000 WB positive control: RAW264.7 cells |
Reactivities | Human, Mouse |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Fusion protein corresponding to a region derived from 378-599 amino acids of human interleukin 18 receptor accessory protein |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 68 kDa |
Gene Name | interleukin 18 receptor accessory protein |
Database Link | |
Background | Interleukin 18 receptor accessory protein; also known as?IL18RAP?and?CDw218b?(cluster of differentiationw218b); is a human?gene. The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP); a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-?B and MAPK8 (JNK) in response to IL18. |
Synonyms | ACPL; CD218b; CDw218b; IL-1R-7; IL-1R7; IL-1RAcPL; IL-18R-beta; IL-18RAcP; IL-18Rbeta; IL18RB |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction |
Documents
Product Manuals |
FAQs |
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