ABCG1 Rabbit Polyclonal Antibody

CAT#: TA322702

Anti-ABCG1 Rabbit Polyclonal Antibody

Product Images

Predicted cell location: Cytoplasm. Positive control: Human breast and colon cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human breast cancer tissue using ABCG1 antibody at dilution 1/25, on the right is treated with the synthetic peptide. (Original magnification:x 200)

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  Predicted cell location: Cytoplasm. Positive control: Human breast and colon cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using ABCG1 antibody at dilution 1/25, on the right is treated with the synthetic peptide. (Original magnification:x200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: ELISA: 1:2000-5000, IHC: 1:25-100
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 349-362 amino acids of human ATP-binding cassette, sub-family G (WHITE), member 1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: ATP binding cassette subfamily G member 1
• Database Link:
  NP_004906
  Entrez Gene 11307 MouseEntrez Gene 85264 RatEntrez Gene 9619 Human
  UniProt ID P45844
• Background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1; MDR/TAP; MRP; ALD; OABP; GCN20; White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport; and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified.
• Synonyms: ABC8; WHITE1

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: ABC transporters