SEL1L Rabbit Polyclonal Antibody

CAT#: TA322674

Anti-SEL1L Rabbit Polyclonal Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using TA322674 (SEL1L Antibody) at dilution 1/25 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using TA322674 (SEL1L Antibody) at dilution 1/25, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human gasrtic cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 561-572 amino acids of human sel-1 suppressor of lin-12-like (C. elegans)
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: SEL1L ERAD E3 ligase adaptor subunit
• Database Link:
  NP_005056
  Entrez Gene 20338 MouseEntrez Gene 314352 RatEntrez Gene 6400 Human
  UniProt ID Q9UBV2
• Background: The protein encoded by this gene is part of a protein complex required for the retrotranslocation or dislocation of misfolded proteins from the endoplasmic reticulum lumen to the cytosol; where they are degraded by the proteasome in a ubiquitin-dependent manner. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Synonyms: PRO1063; SEL1-LIKE; SEL1L1

Reference Data

• Protein Families: Druggable Genome, Transmembrane