ATPase Inhibitory Factor 1 (ATPIF1) Rabbit Polyclonal Antibody
USD 436.00
USD 200.00
USD 867.00
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | WB: 1000-5000 WB positive control: Hela, Jurkat, MCF7 and A431 cells IHC: 50-200 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Fusion protein corresponding to a region derived from 26-106 amino acids of human ATPase inhibitory factor 1 |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 12 kDa |
Gene Name | ATPase inhibitory factor 1 |
Database Link | |
Background | ATPase inhibitor; mitochondrial?is an?enzyme?that in humans is encoded by the?ATPIF1?gene. This gene encodes a mitochondrial ATPase inhibitor. Alternative splicing occurs at this locus and three transcript variants encoding distinct isoforms have been identified. It prevents ATPase from switching to ATP hydrolysis during collapse of the electrochemical gradient; for example during oxygen deprivation ATP synthase inhibitor forms a one to one complex with the F1 ATPase; possibly by binding at the alpha-beta interface. It is thought to inhibit ATP synthesis by preventing the release of ATP. The inhibitor has two oligomeric states; dimer (the active state) and tetramer. |
Synonyms | ATPI; ATPIP; IP |
Reference Data |
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