FZD3 Rabbit Polyclonal Antibody
Anti-FZD3 Rabbit Polyclonal Antibody
Product Datasheet for 'TA322315'
|Recommend Dilution||ELISA: 1:1000-5000, IHC: 1:25-100|
|Reactivity||Human, Mouse, Rat|
|Immunogen||Synthetic peptide corresponding to a region derived from 133-147 amino acids of human frizzled family receptor 3|
|Formulation||PBS pH7.3, 0.05% NaN3, 50% glycerol|
|Purification||Antigen affinity purification|
|Gene Name||frizzled class receptor 3|
|Background||This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown; although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. This gene is a susceptibility locus for schizophrenia.|
|Protein Families||Druggable Genome, GPCR, Transmembrane|
|Protein Pathways||Basal cell carcinoma, Colorectal cancer, Melanogenesis, Pathways in cancer, Wnt signaling pathway|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.