ADAMTS17 Rabbit Polyclonal Antibody

CAT#: TA322062

Anti-ADAMTS17 Rabbit Polyclonal Antibody

Product Images

Predicted band size: 121 kDa. Positive control: NIH/3T3 cell lysate. Recommended dilution: 1/500-2000. (Gel: 8%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/1300 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 hour)

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  Predicted cell location: Cytoplasm. Positive control: Human thyroid cancer tissue. Recommended dilution: 1/50-200 The image on the left is immunohistochemistry of paraffin-embedded human thyroid cancer tissue using ADAMTS17 antibody at dilution 1/60, on the right is treated with the synthetic peptide. (Original magnification:x200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1:2000-5000, WB: 1:500-2000,IHC: 1:50-200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 609-621 amino acids of human ADAM metallopeptidase with thrombospondin type 1 motif, 17
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 121 kDa
• Gene Name: ADAM metallopeptidase with thrombospondin type 1 motif 17
• Database Link:
  NP_620688
  Entrez Gene 233332 MouseEntrez Gene 293004 RatEntrez Gene 170691 Human
  UniProt ID Q8TE56
• Background: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules; including a propeptide region; a metalloproteinase domain; a disintegrin-like domain; and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs; and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by ADAMTS19; another family member. The function of this protein has not been determined.
• Synonyms: FLJ16363; FLJ32769

Reference Data

• Protein Families: Druggable Genome