Beclin 1 (BECN1) Rabbit Polyclonal Antibody

CAT#: TA321594

Anti-BECN1 Rabbit Polyclonal Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-6: Jurkat cell 231 cell NIH/3T3 cell Human fetal brain tissue 293T and Raji cell lysates Primary antibody: TA321594 (BECN1 Antibody) at dilution 1/700 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 1 minute

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  Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TA321594 (BECN1 Antibody) at dilution 1/30 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TA321594 (BECN1 Antibody) at dilution 1/30, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA321594 (BECN1 Antibody) at dilution 1/30 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA321594 (BECN1 Antibody) at dilution 1/30, treated with synthetic peptide. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Jurkat cell, 231 cell, NIH/3T3 cell, Human fetal brain tissue, 293T and Raji cell lysates
  IHC: 50-100
  Positive control: Human prostate cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 50-65 amino acids of Human Beclin-1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 52 kDa
• Gene Name: beclin 1
• Database Link:
  NP_003757
  Entrez Gene 56208 MouseEntrez Gene 114558 RatEntrez Gene 8678 Human
  UniProt ID Q14457
• Background: Beclin-1 is a protein that in humans is encoded by the BECN1 gene.Beclin-1 is also known as autophagy-related gene (Atg) 6. Beclin-1 and its binding partner class III phosphoinositide 3-kinase (PI3K); also named Vps34; which are participates in the regulation of autophagy and has an important role in development; tumorigenesis; and neurodegeneration.
• Synonyms: ATG6; beclin1; VPS30

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Regulation of autophagy