ADFP (PLIN2) Rabbit Polyclonal Antibody

CAT#: TA321279

Anti-PLIN2 Rabbit Polyclonal Antibody

Product Images

Gel: 10%SDS-PAGE Lysate: 40 μg Lane 1-2: Human liver cancer tissue mouse brain tissue Primary antibody: TA321279 (PLIN2 Antibody) at dilution 1/300 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 40 seconds

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  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA321279 (PLIN2 Antibody) at dilution 1/25 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA321279 (PLIN2 Antibody) at dilution 1/25, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA321279 (PLIN2 Antibody) at dilution 1/25 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA321279 (PLIN2 Antibody) at dilution 1/25, treated with synthetic peptide. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Human liver cancer and mouse brain tissue
  IHC: 25-100
  Positive control: Human lung cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 423-437 amino acids of human perilipin 2
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 48 kDa
• Gene Name: perilipin 2
• Database Link:
  NP_001113
  Entrez Gene 11520 MouseEntrez Gene 101055843 MouseEntrez Gene 123 Human
  UniProt ID Q99541
• Background: The protein encoded by this gene belongs to the perilipin family; members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material; and maybe involved in development and maintenance of adipose tissue. However; it is not restricted to adipocytes as previously thought; but is found in a wide range of cultured cell lines; including fibroblasts; endothelial and epithelial cells; and tissues; such as lactating mammary gland; adrenal cortex; Sertoli and Leydig cells; and hepatocytes in alcoholic liver cirrhosis; suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene.
• Synonyms: ADFP; ADRP

Reference Data

• Protein Families: Druggable Genome