Retinoic Acid Receptor alpha (RARA) Rabbit Polyclonal Antibody

CAT#: TA321249

Anti-RARA Rabbit Polyclonal Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA321249 (RARA Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA321249 (RARA Antibody) at dilution 1/40, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA321249 (RARA Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA321249 (RARA Antibody) at dilution 1/40, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human thyroid cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 200-419 amino acids of human retinoic acid receptor, alpha
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: retinoic acid receptor alpha
• Database Link:
  NP_000955
  Entrez Gene 19401 MouseEntrez Gene 5914 Human
  UniProt ID P10276
• Background: This gene represents a nuclear retinoic acid receptor. The encoded protein; retinoic acid receptor alpha; regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development; differentiation; apoptosis; granulopoeisis; and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.
• Synonyms: NR1B1; RAR

Reference Data

• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
• Protein Pathways: Acute myeloid leukemia, Pathways in cancer