Estrogen Related Receptor beta (ESRRB) Rabbit Polyclonal Antibody

CAT#: TA319646

Rabbit Polyclonal ESRRB Antibody

Product Images

Western blot analysis of ESRRB in human heart tissue lysate with ESRRB antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

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  Immunohistochemistry of ESRR8 in human heart tissue with ESRR8 antibody at 5 ug/mL.

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  Immunofluorescence of ESRRB in human heart tissue with ESRRB antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 5 ug/mL, IF: 5 ug/mL
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: ESRRB antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human ESRRB.
• Formulation: ESRRB Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: ESRRB Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: estrogen related receptor beta
• Database Link:
  NP_004443
  Entrez Gene 2103 Human
  UniProt ID O95718
• Background: ESRRB Antibody: The estrogen-related receptor beta (ESRRB) was initially identified in mouse embryonic carcinoma stem cells and was found to be expressed exclusively in trophoblast progenitor cells between days 6.5 and 7.5 post coitum. Recent studies have shown that ESRRB is part of an POU5F1/Oct4-centered protein interaction network in embryonic stem (ES) cells. It is thought to interact with other ES transcription factors such as NANOG within this network, activating POU5F1 transcription and thereby sustaining self-renewal and pluripotency in ES cells.
• Synonyms: DFNB35; ERR2; ERRb; ESRL2; NR3B2

Reference Data

• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors