Ido1 Mouse Monoclonal Antibody [Clone ID: 10.1]

CAT#: TA319542

Mouse monoclonal anti-IDO1 antibody

Antibody Service

 Product Datasheet for 'TA319542'

USD 503.00

2 Weeks

    • 100 ug

Product images


Product Data
Clone Name 10.1
Applications WB
Recommend Dilution ELISA: 1:5000-1:50000, WB: 1:500-1:1500, IHC: 1:100-1:500, IF: 1:50-1:100, IP: 10-100 uL
Reactivity human, mouse
Host Mouse
Clonality Monoclonal
Immunogen Anti-IDO1 (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with fragment of recombinant human and mouse IDO1 protein followed by hybridoma development.
Formulation 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Concentration 1.0 mg/mL
Gene Name indoleamine 2,3-dioxygenase 1
Synonyms IDO|IDO-1|INDO
Note Indoleamine 2, 3-dioxygenase1 (IDO1) is a 41-42 kD intracellular enzyme that catabolizes tryptophan into kynurenine. IDO1 modulates levels of the amino acid tryptophan, which is vital for cell growth, but is also involved in the suppression of the immune response. IDO1 effects on immune suppression are due to decreased tryptophan availability and the generation of tryptophan metabolites, resulting in negative effects on T lymphocytes, including proliferation, function and survival. IDO1 may be involved in the suppression of the immune response to tumors, and blocking the IDO1 pathway may be a potential target for immuno and cancer therapy. IDO1 is expressed in a wide variety of tissues and can be upregulated by interferon gamma and other inflammatory cytokines.
Reference Data
Protein Families Druggable Genome
Protein Pathways Tryptophan metabolism, Metabolic pathways
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.