Annexin A1 (ANXA1) Rabbit Polyclonal Antibody

CAT#: TA308701

Rabbit polyclonal antibody to Annexin A1 (annexin A1)

Product Images

Sample (30 ug of whole cell lysate). A: NIH-3T3. 10% SDS PAGE. TA308701 diluted at 1:10000.

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  Sample (30 ug of whole cell lysate). A: H1299. 10% SDS PAGE. TA308701 diluted at 1:1000.

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  Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using Annexin A1 (TA308701) antibody at 1:500 dilution.

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  Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using Annexin A1 (TA308701) antibody at 1:200 dilution.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:1000-1:10000
• Reactivities: Human (Predicted: Feline, Pig, Rabbit, Rat, Bovine)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 228 of Annexin A1 (Uniprot ID#P04083)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 39 kDa
• Gene Name: annexin A1
• Database Link:
  NP_000691
  Entrez Gene 25380 RatEntrez Gene 301 Human
  UniProt ID P04083
• Background: Annexin I belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity. [provided by RefSeq]
• Synonyms: ANX1; LPC1
• Note: Seq homology of immunogen across species: Cat (93%), Pig (87%), Rabbit (92%), Rat (89%), Bovine (89%)

Reference Data

• Protein Families: Druggable Genome