AP2M1 Rabbit Polyclonal Antibody

CAT#: TA308343

Rabbit Polyclonal antibody to AP2M1 (adaptor-related protein complex 2, mu 1 subunit)

Product Images

Sample (30 ug of whole cell lysate). A:293T. B:HeLa S3. 10% SDS PAGE. TA308343 diluted at 1:500

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  Immunohistochemical analysis of paraffin-embedded N87 xenograft, using AP2M1 (TA308343) antibody at 1:100 dilution.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human (Predicted: Mouse, Rat, Bovine)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment contain a sequence corresponding to a region within amino acids 1 and 150 of AP2M1 (Uniprot ID#Q96CW1)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 50 kDa
• Gene Name: adaptor related protein complex 2 mu 1 subunit
• Database Link:
  NP_001020376
  Entrez Gene 11773 MouseEntrez Gene 116563 RatEntrez Gene 1173 Human
  UniProt ID Q96CW1
• Background: This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
• Synonyms: AP50; CLAPM1; mu2
• Note: Seq homology of immunogen across species: Mouse (100%), Rat (100%), Bovine (100%)

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Endocytosis, Huntington's disease