Mannose Phosphate Isomerase (MPI) Rabbit Polyclonal Antibody

CAT#: TA307934

Rabbit polyclonal antibody to MPI (mannose phosphate isomerase)

Product Images

Sample (30ug whole cell lysate). A: 293T. B: A431. C: H1299. D: HeLa S3. E: Hep G2. F: MOLT4. G: Raji. 10% SDS PAGE. TA307934 diluted at 1:1000

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  MPI antibody detects MPI protein by Western blot analysis. A. 30 ug PC-12 whole cell lysate/extract. B. 30 ug Rat2 whole cell lysate/extract. 10 % SDS-PAGE. MPI antibody (TA307934) dilution: 1:1000

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  Immunohistochemical analysis of paraffin-embedded Gastric CA N87 xenograft, using MPI (TA307934) antibody at 1:100 dilution.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human (Predicted: Mouse, Rat, Bovine)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 150 and 423 of MPI (Uniprot ID#P34949)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 47 kDa
• Gene Name: mannose phosphate isomerase
• Database Link:
  NP_002426
  Entrez Gene 110119 MouseEntrez Gene 300741 RatEntrez Gene 4351 Human
  UniProt ID P34949
• Background: Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib. [provided by RefSeq]
• Synonyms: CDG1B; PMI; PMI1
• Note: Seq homology of immunogen across species: Mouse (84%), Rat (86%), Bovine (92%)

Reference Data

• Protein Families: ES Cell Differentiation/IPS
• Protein Pathways: Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism, Metabolic pathways