EHMT1/GLP (EHMT1) Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | WB |
Recommended Dilution | WB: 1:1000 |
Reactivities | Human (Predicted: Mouse) |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | This EHMT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1145-1174 amino acids from the C-terminal region of human EHMT1. |
Formulation | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration | lot specific |
Purification | This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 138254 Da |
Gene Name | euchromatic histone lysine methyltransferase 1 |
Database Link | |
Background | EHMT1, also known as EUHMTASE1, is a histone methyltransferase. This protein methylates 'Lys-9' of histone H3 in vitro. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT1 is Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle. |
Synonyms | bA188C12.1; Eu-HMTase1; EUHMTASE1; FP13812; GLP; GLP1; KMT1D |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Lysine degradation |
Documents
Product Manuals |
FAQs |
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