FLIP (CFLAR) (Long Form) (C-term) Rabbit Polyclonal Antibody

CAT#: SP1170P

FLIP (CFLAR) (Long Form) (C-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of whole cell lysates from HeLa (H), Jurkat (J) and K562 cell lines probed with Rabbit anti Human FLIP

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  Immunocytochemical staining of Jurkat cells with Rabbit anti Human FLIP

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: Western blot: 1/500 - 1/2000.
  Immunocytochemistry.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Peptide at C-terminus of human FLIPL
• Specificity: This antibody recognises the 55kD FLIPL protein, a FLICE inhibitory protein.
• Formulation: PBS containing 0.02% Sodium Azide
  State: Purified
  State: Liquid purified IgG
• Concentration: lot specific
• Purification: Ion exchange chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: CASP8 and FADD like apoptosis regulator
• Database Link:
  Entrez Gene 8837 Human
  UniProt ID O15519
• Background: FLIP was cloned independently in a number of laboratories, and is also known as Casper, I-FLICE, FLAME-1, CASH and CLARP. FLIP has two death effector domains (DEDs) and a caspase-like domain. It interacts with FADD and caspase-8 and -10, potently inhibiting apoptosis by all known death receptors. FLIP exists in a short form (FLIPS) and a long form (FLIPL). Only FLIPL is recognised by this antibody.
• Synonyms: c-FLIP, CLARP, MRIT, CASH, FLAME-1, CASP8AP1, Usurpin