NCR1 Mouse Monoclonal Antibody [Clone ID: n1D9]

CAT#: SM6004

NCR1 mouse monoclonal antibody, clone n1D9, Purified

Product Images

Profile of PBMC analyzed by Flow Cytometry.

Specifications

Product Data

• Clone Name: n1D9
• Applications: ELISA, FC
• Recommended Dilution: ELISA.
  Western blot (Cell Lysate).
  Flow Cytometry: This product is routinely tested on peripheral blood mononuclear cells (PBMCs) or natural killer(NK) cells. The histogram is an example of the Flow Cytometric analyses.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant Human NKp46 protein (22-255aa) purified from E. coli.
• Specificity: This antibody is specific for NKp46.
• Formulation: PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein-G affinity chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: natural cytotoxicity triggering receptor 1
• Database Link:
  Entrez Gene 9437 Human
  UniProt ID O76036
• Background: A natural cytotoxicity receptor (NCR), NKp46, is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 residue stalk resion, a type I transmembrane domain, and a short cytoplasmic tail. NKp46 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. NKp46 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines.
• Synonyms: NCR1, LY94, NKp46