Cd200 Mouse Monoclonal Antibody [Clone ID: OX-2]
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Specifications
Product Data | |
Clone Name | OX-2 |
Applications | FC, IHC, IP |
Recommended Dilution | Flow Cytometry: 1/50 - 1/100; Use 10µl of the suggested working dilution to label 10e6 cells in 100µl; We recommend the use of SM294A for use in functional studies. Immunoprecipitation. Immunohistochemistry on frozen sections. |
Reactivities | Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Rat thymocyte membrane glycoproteins. Spleen cells from immunised BALB/c mice were fused with cells from the NS1 mouse myeloma cell line. |
Specificity | This antibody recognises the CD200 cell surface antigen, also known as OX-2. This product is routinely tested by flow cytometry on rat thymocytes. |
Formulation | PBS, pH7.4 containing 0.09% Sodium Azide State: Purified State: Liquid purified IgG |
Concentration | lot specific |
Purification | Affinity chromatography on Protein G |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | Cd200 molecule |
Database Link | |
Background | CD200 is a type I membrane glycoprotein, expressed on rat thymocytes, neurons, follicular dendritic cells, endothelium and at low levels on some B cells and smooth muscle cells. Studies have indicated that the CD200-CD200 ligand system is important in the control of macrophage and granulocyte activation and that this antibody blocks OX-2 mediated T cell costimulation. |
Synonyms | OX-2 membrane glycoprotein, MOX1, MOX2, My033 |
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