Mrc1 Rat Monoclonal Antibody [Clone ID: MR5D3]

CAT#: SM1857B

Mrc1 rat monoclonal antibody, clone MR5D3, Biotin

Specifications

Product Data

• Clone Name: MR5D3
• Applications: FC
• Recommended Dilution: Flow Cytometry: Neat - 1/10; Use 10µl of the suggested working dilution to label 10e6 cells in 100µl; The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Chimaeric CRD4-7-Fc protein. Spleen cells from immunised Fischer rats were fused with cells of the Y3 myeloma cell line.
• Specificity: This antibody recognises the mannose receptor, a 175kD type 1 membrane protein that is also known as CD206. Clone MR5D3 has been reported to be non-inhibitory for the binding of the mannose receptor to carbohydrate ligands.
• Formulation: PBS, pH 7.4 containing 0.09% Sodium Azide and 1% Bovine Serum Albumin
  Label: Biotin
  State: Liquid purified IgG
• Concentration: lot specific
• Purification: Affinity chromatography on Protein G
• Conjugation: Biotin
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: mannose receptor, C type 1
• Database Link:
  Entrez Gene 17533 Mouse
  UniProt ID Q61830
• Background: CD206 is expressed on most tissue macrophages, in vitro derived dendritic cells, lymphatic and sinusoidal endothelia.
• Synonyms: Macrophage mannose receptor, CLEC13D, CLEC13DL, MRC1L1