CD35 (CR1) Mouse Monoclonal Antibody [Clone ID: E11]

CAT#: SM1097F

CD35 (CR1) mouse monoclonal antibody, clone E11, FITC

Specifications

Product Data

• Clone Name: E11
• Applications: FC
• Recommended Dilution: Flow Cytometry.
• Reactivities: Human, Monkey
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human acute monocytic leukaemia cells. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
• Specificity: This antibody recognises the CD35 cell surface glycoprotein.
• Formulation: PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer.
  Label: FITC
  State: Liquid purified IgG fraction.
  Label: Fluorescein Isothiocyanate Isomer 1
• Concentration: lot specific
• Purification: Ion Exchange Chromatography.
• Conjugation: FITC
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  This product is photosensitive and should be protected from light.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: complement component 3b/4b receptor 1 (Knops blood group)
• Database Link:
  Entrez Gene 1378 Human
  UniProt ID P17927
• Background: CD35 is a single chain cell surface glycoprotein which exists in four allotypic forms (A,B,C,D) of 190kD, 220kD, 160kD and 250kD respectively. The molecule is expressed by granulocytes, monocytes, B cells and some T cells. Functionally CD35 acts as a receptor for the C3b component of complement.
• Synonyms: Complement receptor type 1, CR1, C3b/C4b receptor