CD9 Mouse Monoclonal Antibody [Clone ID: MM2/57]

CAT#: SM1065R

CD9 mouse monoclonal antibody, clone MM2/57, PE

Product Images

Staining of human peripheral blood platelets with MOUSE ANTI HUMAN CD9:RPE

Specifications

Product Data

• Clone Name: MM2/57
• Applications: FC
• Recommended Dilution: Flow Cytometry: Use 10 µl of Neat-1/2 diluted antibody to label 10e6 cells or 100 µl whole blood.
• Reactivities: Bovine, Canine, Equine, Feline, Human, Porcine, Rabbit
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Human platelet membrane. Spleen cells from immunised BALB/c mice were fused with cells from the SP2/0 mouse myeloma line.
• Specificity: This antibody is a 24kD cell surface glycoprotein expressed by platelets, monocytes, some lymphocytes and endothelial cells. It is a member of the tetraspans gene family.
• Formulation: PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer.
  Label: PE
  State: Lyophilized purified IgG fraction.
  Label: R. Phycoerythrin (RPE)
• Reconstitution Method: Restore with distilled water.
• Purification: Affinity chromatography on Protein A
• Conjugation: PE
• Storage: Prior to and following reconstitution store the antibody undiluted at 2-8°C.
  DO NOT FREEZE!
  This product is photosensitive and should be protected from light.
• Stability: Shelf life: one year from despatch.
• Gene Name: CD9 molecule
• Database Link:
  Entrez Gene 928 Human
  UniProt ID P21926
• Background: CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. It belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). It also regulates cell motility in a variety of cell lines, and appears to be an important regulator of Schwann cell behaviour in peripheral nerve.
• Synonyms: MIC3, TSPAN29, GIG2, p24, Tetraspanin-29, 5H9 antigen