Her2 (ERBB2) Rabbit Polyclonal Antibody

CAT#: DP006

Her2 (ERBB2) rabbit polyclonal antibody, Purified

Product Images

Formalin fixed paraffin embedded human breast carcinoma stained with c-erbB-2 antibody. DP006

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on paraffin embedded sections:
  diluted of 1:25-1:50 in an ABC method (30 minutes at room temperature)
  Although not required, high temperature treatment may enhance the immunostaining in overfixed tissues.
  Recommended Positive Control: Breast carcinoma
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Keyhole limpet hemocyanin conjugated synthetic human peptide c-erbB-2 oncoprotein.
• Specificity: This antibody reacts with the c-erbB-2 oncoprotein, a 190 kD protein.
  Cellular Localization: Cell membrane
• Formulation: containing azide as preservative.
  State: Purified
  State: Liquid purified antiserum
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: erb-b2 receptor tyrosine kinase 2
• Database Link:
  Entrez Gene 2064 Human
  UniProt ID P04626
• Background: The proto-oncogene for c-erbB-2 is located on the human chromosome 17, band 21. It has structural similarities to EGFR. Several studies have indicated that c-erbB-2 may be a good indicator of the prognosis of human carcinomas in the breast, ovary, uterus and gastrointestinal tract.
• Synonyms: HER-2, NEU, p185erbB2, NGL, c-erbB-2, MNL19