CD79A Mouse Monoclonal Antibody [Clone ID: HM57]

CAT#: DM118

CD79A mouse monoclonal antibody, clone HM57, Supernatant

Specifications

Product Data

• Clone Name: HM57
• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Frozen and Paraffin Sections: diluted of 1/15-1/30 in an ABC method (30-60 minutes at room temperature or overnight at 4°C)
  Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining.
  Positive Control: Tonsil.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Synthetic peptide comprising of 202-216 C terminal amino acids part of mb-1 protein.
• Specificity: This antibody reacts specifically with B cells at the pre B cell stage.
  It stains the majority of acute leukemias of precursor B cell type, B cell lymphomas, and some myelomas. The mb-1 polypeptide and B29 polypeptide forms an antigen receptor complex on the B cell, performing signal transaction and phosphorylation functions.
  Cellular Localization: Cell membrane.
• Formulation: State: Supernatant
  State: Liquid Ig fraction
  Stabilizer: 1% BSA
  Preservative: 0.05% Sodium Azide
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: CD79a molecule
• Database Link:
  Entrez Gene 973 Human
  UniProt ID P11912
• Background: It stains majority of acute leukemias of precursor B cell type, B cell lymphomas and some myelomas. The mb-1 polypeptide along with B29 polypeptide forms an antigen receptor complex on the B cell performing signal transaction and phosphorylation functions.
• Synonyms: IGA, MB1, B-Cell marker