Phospholipase A2 IIA (PLA2G2A) Mouse Monoclonal Antibody [Clone ID: OTI1C2]

CAT#: CF808040

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Carrier-free (BSA/glycerol-free) PLA2G2A mouse monoclonal antibody, clone OTI1C2 (formerly 1C2)


Product Datasheet for 'CF808040'


  View other "OTI1C2" antibodies (2)

USD 465.00


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Size
    • 100 ug


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Specifications

Product Data
Clone Name OTI1C2
Applications WB
Recommend Dilution WB 1:2000
Reactivity Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 21-144 of human PLA2G2A(NP_000291) produced in E.coli.
Formulation PBS (pH7.3), 8% Trehalose
Reconstitution Method Reconstitute with PBS (pH7.3). To use this carrier-free antibody for conjugation experiment, we strongly recommend you to perform another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids by affinity chromatography
Predicted Protein Size 13.9 kDa
Gene Name Homo sapiens phospholipase A2 group IIA (PLA2G2A), transcript variant 1, mRNA.
Background The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene. [provided by RefSeq, Sep 2009]
Synonyms MOM1; PLA2; PLA2B; PLA2L; PLA2S; PLAS1; sPLA2
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways alpha-Linolenic acid metabolism, Arachidonic acid metabolism, Ether lipid metabolism, Fc epsilon RI signaling pathway, Glycerophospholipid metabolism, GnRH signaling pathway, Linoleic acid metabolism, Long-term depression, MAPK signaling pathway, Metabolic pathways, Vascular smooth muscle contraction, VEGF signaling pathway

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