NR2C1 Mouse Monoclonal Antibody [Clone ID: OTI4C7]

CAT#: CF803381

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Carrier-free (BSA/glycerol-free) NR2C1 mouse monoclonal antibody, clone OTI4C7 (formerly 4C7)



  View other "OTI4C7" antibodies (2)

USD 465.00


Availability*
In Stock

Size
    • 100 ug


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Specifications

Product Data
Clone Name OTI4C7
Applications IHC, WB
Recommended Dilution WB 1:2000
Reactivity Human, Mouse, Rat
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 1-237 of human NR2C1 (NP_001027458) produced in E.coli.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 51 kDa
Gene Name Homo sapiens nuclear receptor subfamily 2 group C member 1 (NR2C1), transcript variant 2, mRNA.
Background This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
Synonyms TR2
Reference Data
Protein Families Druggable Genome, Nuclear Hormone Receptor, Transcription Factors

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