CX3CL1 Chicken Polyclonal Antibody

CAT#: BP4006

CX3CL1 chicken polyclonal antibody, Aff - Purified

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Frozen Sections: 1 μg/ml (1/200).
  Lower working concentration combined with longer incubation time (e.g. > 2 hours at RT) and choice of blocking reagent and secondary antibody may improve your results.
  Recommended Positive Control: Rat brain.
• Reactivities: Human, Mouse, Rat
• Host: Chicken
• Clonality: Polyclonal
• Immunogen: Synthetic C-terminal peptide coupled to carrier protein.
  The immunizing sequence is > 90% identical with the corresponding mouse and rat sequences.
• Specificity: The antibody reacts with Fractalkine.
• Formulation: PBS, pH 7.2
  State: Aff - Purified
  State: Lyophilized purified IgY fraction
  Preservative: 0.01% Sodium Azide
• Reconstitution Method: Restore with 0.5 ml distilled water to make stock solution.
• Concentration: 0.2 mg/ml (after reconstitution)
• Purification: Affinity Chromatography against peptide coupled to Sepharose
• Conjugation: Unconjugated
• Storage: Store lyophilized at 2-8°C for 6 months or at -20°C long term.
  After reconstitution store the antibody undiluted at 2-8°C for one month
  or (in aliquots) at -20°C long term.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: C-X3-C motif chemokine ligand 1
• Database Link:
  Entrez Gene 6376 Human
  UniProt ID P78423
• Background: Fractalkine is a chemokine present in endothelial cells from several tissues, including brain, liver, and kidney. A high level of fractalkine has also been described in neurons from different regions of the mouse brain. It is the only member of the CX(3)C class of chemokines. Fractalkine contains a chemokine domain (CDF) attached to a membranespanning domain via a mucin-like stalk. However, fractalkine can also be proteolytically cleaved from its membrane-spanning domain to release a freely diffusible form. Fractalkine attracts and immobilizes leukocytes by binding to its receptor, CX(3)CR(1).
• Synonyms: Neurotactin, FKN, NTT, SCYD1