Botulinum neurotoxin type A (light chain) Rabbit Polyclonal Antibody
CAT#: BP2273
Botulinum neurotoxin type A (light chain) rabbit polyclonal antibody, Purified
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Specifications
Product Data | |
Applications | ELISA, WB |
Recommended Dilution | ELISA. Dot Blot. Western blot. |
Reactivities | Clostridium botulinum |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Type A Neurotoxin light chain |
Specificity | This antibody recognizes C. botulinum Type A Neurotoxin Light Chain. |
Formulation | 1xPBS, pH 7.2 containing 20% Glycerol State: Purified State: Liquid purified IgG fraction Preservative: None |
Concentration | lot specific |
Purification | Protein G Sepharose Chromatography |
Conjugation | Unconjugated |
Storage | Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Database Link | |
Background | Clostridium botulinum neurotoxins are zinc-dependent proteases that block the release of acetylcholine from peripheral cholinergic nerve endings by targeting specific membrane proteins including synaptosomal-associated proteins (SNAP), vesicle-associated membrane proteins (VAMP), and syntaxins. Neurotoxin A is characteristically associated with human botulism and known to target and hydrolyse the 197-Gln-|-Arg-198 bond of SNAP-25. |
Synonyms | BoNT/A, Clostridium botulinum Toxin A, Bontoxilysin-A, BOTOX |
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