Cyclosporin A Mouse Monoclonal Antibody [Clone ID: 4A3 (CSZ.22)]
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Specifications
Product Data | |
Clone Name | 4A3 (CSZ.22) |
Applications | ELISA |
Recommended Dilution | ELISA. |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Cyclosporin A conjugated to an HMW carrier |
Specificity | This antibody recognizes Cyclosporin A, a widely-used immunosuppressant drug from the fungus Tolypocladium inflatum. |
Formulation | PBS State: Purified State: Liquid (0.45 µm filtered) purified IgG fraction Preservative: 0.09% Sodium Azide |
Concentration | lot specific |
Purification | Affinity Chromatography on Protein G |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Background | Cyclosporin is used to prevent rejection following solid organ and bone marrow transplantation . It has been estimated that cyclosporine is given to more than 90% of children who have received a kidney transplant in the United States. In addition, the ability of cyclosporin to inhibit T-cell activation has been shown to have a role in the treatment of diseases such as nephrotic syndrome, refractory Crohn's disease and ulcerative colitis, biliary cirrhosis, aplastic anemia, rheumatoid arthritis, myasthenia gravis, and dermatomyositis. |
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