beta 2 Microglobulin (B2M) Mouse Monoclonal Antibody [Clone ID: B2M-01]

CAT#: BM604PE

beta 2 Microglobulin (B2M) mouse monoclonal antibody, clone B2M-01, PE

Product Images

Western blot analysis (non-reducing conditions) of whole cell lysate of various cell lines using anti-human β2-microglobulin. Lane 1: RAJI human Burkitt lymphoma cell line Lane 2: EL4 mouse lymphoblastic lymphoma cell line Lane 3: U937 human histiocytic lymphoma cell line

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  Surface staining of b2-microglobulin in human peripheral blood with anti-b2-microglobulin (B2M-01) PE.

Specifications

Product Data

• Clone Name: B2M-01
• Applications: FC, WB
• Recommended Dilution: Flow Cytometry: 1 μg/ml.
  Positive Control: Peripheral blood lymphocytes.
  Negative Control: DAUDI human Burkitt lymphoma cell line, erythrocytes.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Purified human beta2-microglobulin
• Specificity: This antibody reacts with beta2-microglobulin (beta2M) associated with cell-surface MHC Class I molecules and other membrane antigens as well as with soluble beta2-microglobulin. Beta2M is a 12 kDa Ig like glycoprotein expressed on lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells and epithelial cells. It is absent on erythrocytes.
• Formulation: Phosphate buffered saline (PBS) solution containing 15mM sodium azide
  Label: PE
  State: Liquid purified Ig fraction
  Label: Conjugated with R-Phycoerythrin under optimum conditions. The conjugate is purified by size-exclusion chromatography.
• Concentration: lot specific
• Purification: Size-Exclusion Chromatography
• Conjugation: PE
• Storage: Store the antibody undiluted at 2-8°C.
  DO NOT FREEZE!
  This product is photosensitive and should be protected from light.
• Stability: Shelf life: one year from despatch.
• Gene Name: beta-2-microglobulin
• Database Link:
  Entrez Gene 567 Human
  UniProt ID P61769
• Background: Beta2-microglobulin non-covalently associates with the 44 kDa alpha chain to forms the HLA Class I antigen complex. Human beta2-microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes.
• Synonyms: B2M, Beta-2 microglobulin, Beta 2 microglobulin

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Antigen processing and presentation