LRP1 Mouse Monoclonal Antibody [Clone ID: 5A6]

CAT#: BM5514

LRP1 mouse monoclonal antibody, clone 5A6, Purified

Specifications

Product Data

• Clone Name: 5A6
• Applications: FC, IF, IHC, WB
• Recommended Dilution: Immunoblotting.
  Flow Cytometry.
  Immunofluorescence.
  Immunohistochemistry (Dilute 1/20).
  Neutralizing effects of 5A6 have also been reported (cf. Basu et al., 2001).
• Reactivities: Hamster, Human, Mouse, Rabbit, Rat
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Human LRP/alpha2MR.
• Specificity: This monoclonal antibody 5A6 specifically reacts with the 85 kD beta-chain of LRP/alpha2MR which is expressed in a restricted spectrum of cell types (for a recent review cf. Herz & Strickland). A strong immunohistochemical reaction is seen in hepatocytes, tissue macrophages, subsets of neurones and astrocytes in the central nervous system, fibroblasts, smooth muscle cells, and monocyte-derived foam cells in atherosclerotic lesions in the arterial wall.
  The antibody can also be used for the characterization of a subset of myelomonocytic subtypes of chronic and acute leukemia (CD 91).
  Cross-reacts with rabbit LDL receptor-related protein (LRP) or mouse LRP.
• Formulation: Final solution contains 0.5% BSA in PBS buffer, pH 7.4
  State: Purified
  State: Lyophilzed purified Ig fraction.
• Reconstitution Method: Restore in 1 ml dist. water
• Purification: Affinity Chromatography on Protein A.
• Conjugation: Unconjugated
• Storage: For extended storage keep in aliquots at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: LDL receptor related protein 1
• Database Link:
  Entrez Gene 4035 Human
  UniProt ID Q07954
• Synonyms: A2MR, APR, APOER