PKMYT1 pSer83 Rabbit Polyclonal Antibody
Other products for "PKMYT1"
Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | Immunohistochemistry on paraffin sections: 1:50~1:100 . |
Reactivities | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Peptide sequence around phosphorylation site of Serine 83(R-V-S(p)-F-R) derived from Human MYT1 (KLH-conjugated) |
Specificity | The antibody detects endogenous levels of MYT1 only when phosphorylated at serine 83. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol State: Aff - Purified State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Affinity chromatography using epitope-specific peptide |
Conjugation | Unconjugated |
Storage | Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 54 kDa |
Gene Name | protein kinase, membrane associated tyrosine/threonine 1 |
Database Link | |
Background | The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported. |
Synonyms | Myt1 kinase, MYT1 |
Reference Data |
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