Stathmin 1 (STMN1) pSer62 Rabbit Polyclonal Antibody

CAT#: AP55746PU-N

Stathmin 1 (STMN1) pSer62 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of extracts from COS cells treated with nocodazole using STMN1 (Phospho-Ser62) Antibody #.The lane on the right is treated with the antigen-specific peptide.

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  Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STMN1 (Phospho-Ser62) antibody (left)or the same antibody preincubated with blocking peptide (right).

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: 1:500~1:1000.
  Immunohistochemistry on paraffin sections: 1:50~1:100.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Peptide sequence around phosphorylation site of Serine 62(R-R-K(p)-S-H) derived from Human STMN1 (KLH-conjugated)
• Specificity: The antibody detects endogenous levels of STMN1 only when phosphorylated at serine 62.
• Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography using epitope-specific peptide
• Conjugation: Unconjugated
• Storage: Upon receipt, store undiluted (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 22 kDa
• Gene Name: stathmin 1
• Database Link:
  Entrez Gene 3925 Human
  UniProt ID P16949
• Background: This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Alternatively spliced transcript variants encoding the same protein have been identified.
• Synonyms: LAP18, OP18, Phosphoprotein p19, pp19, Leukemia-associated phosphoprotein p18, Oncoprotein 18, Op18, pp17, Prosolin, Metablastin, Protein Pr22