Cardiac Troponin T (TNNT2) Rabbit Polyclonal Antibody

CAT#: AP55359SU-N

Cardiac Troponin T (TNNT2) rabbit polyclonal antibody, Serum

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution:

  ELISA.
  Western Blot: 1/500-1/5000.
  Immunohistochemistry: 1/200-1/1000.

• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide derived from C-terminal domain of Human Troponin
• Specificity: Reacts with Human 36 kDa TnTc.
• Formulation: State: Serum
  State: Lyophilized serum
  Preservative: None
• Reconstitution Method: Restore in distilled water.
• Conjugation: Unconjugated
• Storage:

  Prior to reconstitution store the antibody at -20°C.
  Store reconstituted antibody at 2-8°C for one month or (in aliquots) at -20°C for longer
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: troponin T2, cardiac type
• Database Link:
  Entrez Gene 7139 Human
  UniProt ID P45379
• Background: Cardiac Troponin T, a 36kDa protein, is the tropomyosin binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations within the protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the gene undergo alternative splicing that results in many tissue specific isoforms.
• Synonyms: cTnT, TnTc, TNNT2