Paired box protein Pax-7 (PAX7B) Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | ELISA, IHC, WB |
Recommended Dilution | ELISA. Western Blot: 1/200-1/1000. Immunohistochemistry: 1/50-1/200. |
Reactivities | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide derived from C-terminal domain of PAX7B protein |
Specificity | Reacts with Human 55 kDa protein. Cross reacts with PAX7B protein from Mouse, Rat and other species. |
Formulation | State: Serum State: Lyophilized powder Preservative: None |
Reconstitution Method | Restore in distilled water. |
Conjugation | Unconjugated |
Storage | Prior to reconstitution store the antibody at -20°C. |
Stability | Shelf life: one year from despatch. |
Database Link | |
Background | This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box gene 7 is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Alternative splicing in this gene has produced two known products but the biological significance of the variants is unknown. |
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