Diffuse panbronchiolitis critical region protein 1 (DPCR1) (pan) Rabbit Polyclonal Antibody

CAT#: AP54894SU-N

Diffuse panbronchiolitis critical region protein 1 (DPCR1) (pan) rabbit polyclonal antibody, Serum

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution:

  ELISA.
  Western Blot: 1/500-1/2000.

• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide derived from Human N-terminal region of Diffuse Panbronchiolitis Critical Region protein 1 (DPCR1)
• Specificity: Reacts with 38 kDa DPCR1 protein.
• Formulation: State: Serum
  State: Lyophilized serum
  Preservative: None
• Reconstitution Method: Restore in 0.2 ml distilled water.
• Conjugation: Unconjugated
• Storage: Store lyophilized at 2-8°C for 6 months or at -20°C long term.
  After reconstitution store the antibody undiluted at 2-8°C for one month
  or (in aliquots) at -20°C long term.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: diffuse panbronchiolitis critical region 1
• Database Link:
  Entrez Gene 135656 Human
  UniProt ID Q3MIW9
• Background: DPCR1 (diffuse panbronchiolitis critical region 1), also known as PBLT, is a 517 amino acid single-pass type I membrane protein that exists as 2 alternatively spliced isoforms. Expressed in adult small intestine, uterus, esophagus, lung, kidney, testis, rectum, stomach, cervix and skin, DPCR1 has also been observed in fetal kidney, lung and heart. The gene encoding DPCR1 maps to a region on chromosome 6 that is shared by seven other genes, which have been linked to diffuse panbronchiolitis. Chromosome 6 contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.
• Synonyms: C6orf37, PBLT