TRPC1 (C-term) Rabbit Polyclonal Antibody

CAT#: AP54359PU-N

TRPC1 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

TRPC1 Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35 ug/lane). This demonstrates the TRPC1 antibody detected the TRPC1 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:1;000.
  Western blot: 1:100~500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 764-793 amino acids from the C-terminal region of human TRPC1
• Specificity: This antibody detects TRPC1 / TRP1 (C-term).
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: transient receptor potential cation channel subfamily C member 1
• Database Link:
  Entrez Gene 7220 Human
  UniProt ID P48995
• Background: TRPC1 belongs to the transient receptor potential (TRP) superfamily of cation channels. TRP cation channels are involved in diverse physiologic processes, including receptor- and store-operated Ca(2+) entry, mineral absorption, and cell death. They also function as sensors for pain, heat, cold, sound, stretch, and osmotic changes (Zhang et al., 2009 [PubMed 19193631]).
• Synonyms: Transient receptor protein 1, TRP-1
• Note: Molecular Weight: 91212 Da

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane
• Protein Pathways: Calcium signaling pathway, Huntington's disease, Parkinson's disease