TEC (N-term) Rabbit Polyclonal Antibody

CAT#: AP54214PU-N

TEC (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

TEC Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35 ug/lane). This demonstrates the TEC antibody detected the TEC protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1;000.
  Western blot: 1/1000.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 25-55 amino acids from the N-terminal region of Human TEC
• Specificity: This antibody detects Human TEC (N-term). Other species not tested.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) Sodium Azide
• Concentration: lot specific
• Purification: Protein A column followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 73581 Da
• Gene Name: tec protein tyrosine kinase
• Database Link:
  Entrez Gene 7006 Human
  UniProt ID P42680
• Background: TEC belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
• Synonyms: PSCTK4

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: T cell receptor signaling pathway