SNX13 (C-term) Rabbit Polyclonal Antibody

CAT#: AP53971PU-N

SNX13 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis in NCI-H292, Hela cell line lysates (35ug/lane) using Sorting nexin-13 (SNX13) antibody. (C-term).This demonstrates the SNX13 antibody detected the SNX13 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: This antibody is suitable for Western blotting.
  The suggested dilution is: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 779-807aa) of human Sorting nexin-13 (SNX13).
• Specificity: This antibody detects human SNX13 at C-term.
• Formulation: PBS with 0.09% (W/V) Sodium Azide.
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Purified through a protein A column; followed by peptide affinity purification.
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: sorting nexin 13
• Database Link:
  Entrez Gene 23161 Human
  UniProt ID Q9Y5W8
• Background: SNX13 gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.
• Synonyms: KIAA0713
• Note: Molecular Weight: 112189 Da

Reference Data

• Protein Families: Druggable Genome, Transmembrane