SNURPORTIN1 (SNUPN) (Center) Rabbit Polyclonal Antibody

CAT#: AP53970PU-N

SNURPORTIN1 (SNUPN) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis in A375 cell line lysates (35ug/lane) using Snurportin-1 (SNUPN) antibody. This demonstrates the SNUPN antibody detected the SNUPN protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: This antibody is suitable for Western blotting. The suggested dilution is: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region ( between 199-228aa) of human Snurportin-1 (SNUPN).
• Specificity: This antibody detects Snurportin-1 (SNUPN).
• Formulation: PBS with 0.09% (W/V) Sodium Azide.
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Purified through a protein A column; followed by peptide affinity purification.
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: snurportin 1
• Database Link:
  Entrez Gene 10073 Human
  UniProt ID O95149
• Background: The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.
• Synonyms: Snurportin1, RNUT1, SPN1, KPNBL
• Note: Molecular Weight: 41143 Da