PPP1R14C (C-term) Rabbit Polyclonal Antibody

CAT#: AP53404PU-N

PPP1R14C (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of PP1R14C Antibody (C-term) in mouse heart tissue lysates (35ug/lane). This demonstrates the PP1R14C antibody detected the PP1R14C protein (arrow).

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  Formalin fixed and paraffin embedded human brain tissue reacted with PP1R14C Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Immunohistochemistry on Paraffin Sections: 1/10-1/50.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 133-163 amino acids from the C-terminal region of human PP1R14C.
• Specificity: This antibody recognizes Human and Mouse PP1R14C (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: protein phosphatase 1 regulatory inhibitor subunit 14C
• Database Link:
  Entrez Gene 76142 MouseEntrez Gene 81706 Human
  UniProt ID Q8TAE6
• Background: The degree of protein phosphorylation is regulated by a balance of protein kinase and phosphatase activities. Protein phosphatase-1 (PP1; see MIM 176875) is a signal-transducing phosphatase that influences neuronal activity, protein synthesis, metabolism, muscle contraction, and cell division. PPP1R14C is an inhibitor of PP1 (Liu et al., 2002 [PubMed 11812771]). [supplied by OMIM].
• Synonyms: KEPI, NY-BR-81
• Note: Molecular Weight: 17843 Da

Reference Data

• Protein Families: Druggable Genome