Protocadherin beta 12 (PCDHB12) (C-term) Rabbit Polyclonal Antibody
CAT#: AP53207PU-N
Protocadherin beta 12 (PCDHB12) (C-term) rabbit polyclonal antibody, Aff - Purified
Other products for "Protocadherin beta 12"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | This antibody is suitable for immunohistochemistry on paraffin sections and Western blotting. |
Reactivities | Human |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 765-795aa) of human PCDHB12. |
Specificity | This antibody detects human PCDHB12 at C-term. |
Formulation | PBS with 0.09% (W/V) Sodium Azide. State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Purified through a protein A column; followed by peptide affinity purification. |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Gene Name | protocadherin beta 12 |
Database Link | |
Background | The PCDHB12 gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. |
Synonyms | Protocadherin beta-12, PCDH-beta-12 |
Note | Molecular Weight: 86770 Da |
Reference Data | |
Protein Families | Transmembrane |
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