NYX (N-term) Rabbit Polyclonal Antibody

CAT#: AP52981PU-N

NYX (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of Nyctalopin Antibody (N-term) in HL-60 cell line lysates (35ug/lane). NYX (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 59~89 amino acids from the N-terminal region of Human Nyctalopin.
• Specificity: This antibody recognizes Human Nyctalopin (N-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: nyctalopin
• Database Link:
  Entrez Gene 60506 Human
  UniProt ID Q9GZU5
• Background: The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB. [provided by RefSeq].
• Synonyms: NYX, CLRP
• Note: Molecular Weight: 52000 Da

Reference Data

• Protein Families: Secreted Protein, Transmembrane