KAT2A (C-term) Rabbit Polyclonal Antibody

CAT#: AP52291PU-N

KAT2A (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of KAT2A / GCN5L2 Antibody (C-term) in UM cell line lysates (35ug/lane). This demonstrates the KAT2A antibody detected the KAT2A protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 610-638 amino acids from the C-terminal region of Human KAT2A / GCN5L2
• Specificity: This antibody recognizes Human KAT2A / GCN5L2 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: lysine acetyltransferase 2A
• Database Link:
  Entrez Gene 2648 Human
  UniProt ID Q92830
• Background:
  KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).
• Synonyms: Histone acetyltransferase KAT2A, Histone acetyltransferase GCN5, HsGCN5, HGCN5, Lysine acetyltransferase 2A, STAF97
• Note: Molecular Weight: 93926 Da

Reference Data

• Protein Families: Transcription Factors
• Protein Pathways: Notch signaling pathway